Intramolecular [3 + 2] annulation of allenylsilane-enes: Direct synthesis of highly strained trans-fused 5/5 ring systems

LV, N.; Han, J.-C.; Zhang P.; Huang, Y.-R.; Xu, Z.-X.; Xu, K.-H.; Wang X-F.; Li, X.; Chung, L.-W.; Li, C.-C.*

Chem, 2023.  [doi]

Total Synthesis of abeo-Steroids via Cycloaddition Strategy

Min, L.; Zhong, L.-P.; Li, C.-C.*

Acc. Chem. Res., 2023, 56, 2378.  [doi]

Total Synthesis of (±)- and (−)-Daphnillonin B

Zou, Y.-P.; Lai, Z.-L.; Zhang, M.-W.;  Peng, J.-Z.; Ning, S.; Li, C.-C.*

J. Am. Chem. Soc., 2023, 145, 10998.  [doi]

Strategies and Lessons Learned from Total Synthesis of Taxol

Min, L.; Han, J.-C.; Zhang, W.; Gu, C.-C.; Zou, Y.-P.; Li, C.-C.*

Chem. Rev., 2023, 123, 4934.  [doi]

Synthesis of Spirotricyclic Core of Bonnadiene

Lin, X.-H.; Huang, Y.; Min, L.;* Li, C.-C.*

Org. Lett., 2023, 25, 1156.  [doi]

Asymmetric Total Synthesis of Twin Bufogargarizins A and B

Zhong, L.-P.; Feng, R.; Wang, J.-J.; Li, C.-C.*

J. Am. Chem. Soc., 2023, 145, 2098.  [doi]

• Highlighted in ChemistryViews, 01/2023

•  Highlighted in X-MOL, 01/2023

• Top 20 Most Accessed Article in 02/2023

•  Highlighted in HUAXUEJIA (化学加), 01/2023

•  Highlighted in Synfacts, 03/2023 (Synfact of the Month)

Total Synthesis of Yuzurine-type Alkaloid Daphgraciline

Li, L.-X.; Min, L.; Yao, T.-B.; Ji, S.-X.; Qiao, C.; Tian, P.-L.; Sun, J.;* Li, C.-C.*

J. Am. Chem. Soc., 2022, 144, 18823.  [doi]

•  Highlighted in X-MOL, 10/2022.

•  Top 5 Most Read Article in 10-11/2022.

•  Highlighted in Synfacts, 12/2022 (Synfact of the Month).

Asymmetric Total Syntheses of Hypoestin A, Albolic Acid, and Ceroplastol II

Wang, Y-Q.; Xu, K.-H.; Min, L.; Li, C.-C.*

J. Am. Chem. Soc., 2022, 144, 10162.  [doi]

• Highlighted in ChemistryViews,  06/2022

• Highlighted in HUAXUE JIA (化学加),  06/2022

• Highlighted in Synfacts, 2022, 18, 0942

• Highlighted in Org. Chem. Highlights, 01/2023

Synthesis of Various Bridged Ring Systems via Rhodium-Catalyzed Bridged (3+2) Cycloadditions

He, Y-T.; Li, L.-X.; Lin, X.-H.; Hou, B-L.*; Li, C.-C.*

Org. Lett., 2021. 24, 186, [doi]

Synthesis of the Bridged [5-7-7] Tricyclic Core of Eurifoloid A

Hou, B-L.; Li, L.-X.; Li, C.-C.*

Org. Lett., 2021. 23, 7771, [doi]

Asymmetric Total Synthesis of Taxol

Hu, Y.-J.; Gu, C.-C.; Wang, X-F.; Min, L.; Li, C.-C.*

J. Am. Chem. Soc., 2021, 143, 17862.  [doi]

• Highlighted in SUSTech News, 10/2021

• Highlighted in HUAXUE JIA (化学加), 10/2021

• Highlighted in Rationalscience  (微信公众号：研之成理)，10/2021

• Highlighted in NSFC, 10/2021

• Highlighted in CBG 资讯, 10/2021

• Highlighted in Synfacts, 2022, 18, 5

• Highlighted in Chin. J. Org. Chem, 2021

• Top 15 Most Accessed Article in 10/2021-now

• Highlighted in Org. Chem. Highlights, 04/2022

Facile generation of bridged medium-sized polycyclic systems by rhodium-catalysed intramolecular (3+2) dipolar cycloadditions

Hou, B-L.; Jonathan J. Wong.; Lv, N.; Wang, Y-Q.; Houk, K. N.*; Li, C.-C.*

Nat. Comm., 2021, 12, 5239.  [doi]

• Highlighted in NSFC, 09/2021

• Highlighted in CBG 资讯, 09/2021

• Highlighted in SUSTech News, 09/2021

• Highlighted in Rationalscience  (微信公众号：研之成理)，09/2021

• Editors' Highlights, 09/2021

• Highlighted in Org. Chem. Highlights, 08/2022

Synthesis of natural products containing highly strained trans-fused bicyclo[3.3.0]octane: historical overview and future prospects

 Zhang, W.; Li, L-Z.; Li, C.-C.*

Chem. Soc. Rev., 2021, 50, 9430.  [doi]

• Highlighted in CBG 资讯, 08/2021

• Highlighted in SUSTech News, 08/2021

Rhodomentosones A and B: Two Pairs of Enantiomeric Phloroglucinol Trimers from Rhodomyrtus tomentosa and Their Asymmetric Biomimetic Synthesis

 Deng, L.-M.; Hu, L-J.; Yang-Ting-Zhi Bai.; Wang, J.; Qin, G.-Q.; Song, Q.-Y.; Su, J.-C.; Huang, X.-J.; Jiang, R.-W.; Tang, W.; Li, Y.-L.; Li, C.-C*.; Ye, W.-C*.;  Wang, Y

Org. Lett., 2021. 23, 4499, [doi]

Enantioselective Total Synthesis of Cerorubenic Acid-III via Type II [5+2] Cycloaddition Reaction

Liu, X.; Liu, J.-Y.; Wu, J.-L.; Li, C.-C.*

J. Org. Chem., 2021, 86, 11125, [doi]

Stable Axially Chiral Isomers of Arylnaphthalene Lignan Glycosides with Antiviral Potential Discovered from Justicia procumbens

Zhao, Y.; Ku, C.-F.; Xu, X.-Y.; Nga-Yi Tsang.; Zhu, Y.; Zhao, C.-L.; Liu, K.-L.; Li, C.-C.; Rong, L.-J.; Zhang, H.-J.*

J. Org. Chem., 2021, 86, 5568.  [doi]

Recent advances in the total synthesis of vinigrol

Min, L.; Li, C.-C.*

Chinese Science Bulletin., 2021,  [doi]

Recent advances in total syntheses of natural products containing the benzocycloheptane motif

Fan, J.-H.; Hu, Y.-J.; Li, L.-X.; Wang, J.-J.; Li, S.-P.; Zhao, J*,; Li, C.-C.*

Nat. Prod. Rep., 2021, 38, 1821.  [doi]

Evolution of Routes for Asymmetric Total Synthesis of Cyclocitrinol Enabled by Type II [5+2] Cycloaddition

Wu, J.-L.; Liu, J.-Y;* Fan, J.-H.; Xie, Z.-D.; Qin, H.-K.; Li, C.-C.*

Chin. J. Chem., 2021, 39, 1247.  [doi] 

Asymmetric Total Synthesis of Phomarol

Fan, J.-H.; Wang, J.-J.; Li, F.; Wang, G.; Guo, Q.; Chung, L.-W.; Li, C.-C.*

CCS Chem., 2021, 3, 348.  [doi]

• Highlighted in X-MOL, 2021

• Highlighted in CBG 资讯, 2021

• Highlighted in SUSTech News, 2021

Asymmetric Total Synthesis of the Highly Strained Acetoxyprobotryane-diol

Zhang, W.; Zhou, Z.-X.; Zhu, X.-J.; Sun, Z.-H.; Dai, W.-M.; Li, C.-C.*

J. Am. Chem. Soc., 2020, 142, 19868.  [doi]

• Highlighted in X-MOL, 11/2020

• Highlighted in HUAXUE JIA (化学加), 11/2020 

• Highlighted in CBG 资讯, 11/2020

• Highlighted in SUSTech News, 12/2020

• Highlighted in Synfacts, 2021, 17, 139. 

• Highlighted in Org. Chem. Highlights, 08/2021.

Synthetic Applications of Type II Intramolecular Cycloadditions

Min, L.; Hu, Y.-J.; Fan, J.-H.; Zhang, W.; Li, C.-C.*

Chem. Soc. Rev., 2020, 49, 7015.  [doi]

• Highlighted in HUAXUE JIA, 09/2020.

• Highlighted in SUSTech News, 09/2020.

Synthetic Study toward the Total Synthesis of Lycoclavatumide

Wang, X.-F.; Bin Wang*.; Li, C.-C.*

Org. Lett., 2020.  [doi]

Collective Total Synthesis of ent-Kaurane Diterpenoids (Highlight)

Min, L.; Li, C.-C.*

Chin. J. Org. Chem., 2020, 40, 3007.  [doi]

Discovery and Biomimetic Synthesis of a Phloroglucinol‐Terpene Adduct Collection from Baeckea frutescens and Its Biogenetic Origin Insight

Luo, S.‐L.; Hu. L.‐J. ; Huang, X.‐J.; Su,J.‐C.; Xue‐Hua Shao.; Lei Wang.; Han‐Hong Xu.; Li, C.-C.*; Ying Wang.*; Wen‐Cai Ye.*

Chem. Eur. J., 2020, 26, 11104.  [doi]

Asymmetric Total Synthesis of Bufospirostenin A

Cheng, M.; Zhong, L.; Gu, C.-C.; Zhu, X.-J.; Chen, B.; Liu, J.-S.; Wang, L*.; Ye, W.-C*.; Li, C.-C.*

J. Am. Chem. Soc., 2020, 142, 12602.  [doi]

• Highlighted in NANOER, 07/2020.

• Highlighted in OrgChemNews, 07/2020. 

• Highlighted in X-MOL, 07/2020.

• Highlighted in HUAXUE JIA, 07/2020.

• Highlighted in CBG, 07/2020.

• Highlighted in SUSTech News, 07/2020.

• Highlighted in Liang 's Medicinal Chemistry, 07/2020.

• Highlighted in Total Synthesis, 08/2020.

• Top 5 Most Read Article in 07-08/2020.Top5.pdf

Recent Advances in the Total Synthesis of Natural Products Containing Eight-Membered Carbocycles (2009−2019)

Hu, Y.-J.; Li, L.-X.; Han, J.-C.; Min, L.; Li, C.-C* 

Chem. Rev., 2020, 120, 5910.  [doi]

Unusual KIE and Dynamics Effects in the Fe-catalyzed Hetero-Diels-Alder Reaction of Unactivated Aldehydes and Dienes

Yang, Y.; Zhang, X.; Zhong, L.; Lan, J.; Li, X.; Li, C.-C.; Chung, L.-W.

Nat. Comm., 2020, 11 , 1850.  [doi]

Leptosperols A and B, Two Cinnamoylphloroglucinol−Sesquiterpenoid Hybrids from Leptospermum scoparium: Structural Elucidation and Biomimetic Synthesis

Gu, J.; Wang, W.; Chen, J.; Liu, J.; Li, N.; Cheng, M.; Hu, L.; Li, C.-C.*; Ye, W.-C.*; Wang, L.* 

Org. Lett., 2020, 22, 1796.   [doi]  

Total Synthesis of Natural Products with Bridged Ring Systems via Type II [5+2] Cycloaddition

Min, L.; Liu, X.; Li, C.-C.*

Acc. Chem. Res., 2020, 53, 703.  [doi]

• Highlighted in HUAXUE JIA, 02/2020. 

Total Synthesis of Natural Products Containing a Bridgehead Double Bond

Liu, J.; Liu, X.; Wu, J.; Li, C.-C.* 

Chem., 2020, 6, 579.  [doi]

Asymmetric Total Synthesis of (−)-Vinigrol

Min, L.; Lin, X.; Li, C.-C.*

J. Am. Chem. Soc., 2019, 141, 15773.  [doi] 

• Highlighted in Synfacts, 2019, 15, 1347.

• Highlighted in SUSTech NEWS, 09/2019.

• Top 5 Most Accessed Article in 10/2019. Top5.pdf 

• Highlighted in HUAXUE JIA, 10/2019. 

• Highlighted in  Liang's  Medicinal chemistry, 10/2019.

• Highlighted in Chemical Science News, 09/2019.

• Highlighted in ChemistryViews, 10/2019.

• Highlighted in NSFC Center for Science Communication, 10/2019.

• Highlighted in Org. Chem. Highlights, 07/2020.

Asymmetric Total Synthesis of Cerorubenic Acid-III

Liu, X.; Liu, J.; Wu, J.; Huang, G.; Liang, R.; Chung, L.-W.; Li, C.-C.* 

J. Am. Chem. Soc., 2019, 141, 2872.  [doi] 

• Top 5 Most Accessed Article in 03/2019. 

• Highlighted in Synfacts, 05/2019.  

• Highlighted in HUAXUE JIA, 02/2019.  

• Highlighted in X-MOL, 02/2019.  

• Highlighted in Chin. J. Org. Chem, 2019.  

• Highlighted in SUSTech NEWS, 02/2019.   

 Collective total synthesis of botryanes

Qiao, C.; Zhang, W.; Han, J.; Dai, W.-M.; Li, C.-C.*

Tetrahedron.,  2019, 75, 1739.  [doi] 

Synthesis of the C6–C18 bis-tetrahydrofuran fragment of the proposed structure of iriomoteolide-2a via stepwise double SN2 cyclization reactions

Zhang, W.; Ma, H.; Li, C.-C.; Dai, W.-M.*   

Tetrahedron., 2019, 75, 1795.  [doi]

 Isolation, Structure Elucidation, and Total Synthesis of Myrtuspirone A from Myrtus communis

Cheng, M.; Yang, X.; Cao, J.; Liu, C.; Zhong, L.; Wang, Y.; You, X.; Li, C.-C.*; Wang, L.*; Ye, W.-C.*;   

Org. Lett., 2019, 21, 1583.  [doi]

Asymmetric Synthesis of the Tetracyclic Core of Bufogargarizin C by an Intramolecular [5+2] Cycloaddition

Fan, J.-H.; Hu, Y.-J.; Guo, Q.; Li, S.; Zhao, J.*; Li, C.-C.*  

Org. Chem. Front., 2019, 6, 22.  [doi]

Synthetic Study toward the Total Synthesis of Taxezopidines A and B

Hu, Y.-J.; Fan, J.-H.; Li, S.; Zhao, J.*; Li, C.-C.*  

Org. Lett., 2018, 20, 5905.  [doi]

Asymmetric Total Synthesis of Cyclocitrinol

Liu, J.; Wu, J.; Fan, J.-H.; Yan, X.; Mei, G.; Li, C.-C.* 

J. Am. Chem. Soc., 2018, 140, 5365.  [doi]  

• Top 5 Most Read Article in 04-05/2018. 

• Highlighted in SUSTech NEWS, April, 2018. 

• Highlighted in HUAXUE JIA, April, 2018.  

• Highlighted in X-MOL, July, 2018.  

• Highlighted in Chin. J. Org. Chem., August, 2018.

Asymmetric Total Syntheses of Callistrilones B, G and J

Hu, L.; Cheng, M.; Cao, J.; Zhong, L.; Hu, Y.; Wang, Y.; 

Wang, L.*; Ye, W.-C.*; Li, C.-C.* 

Org. Chem. Front., 2018, 5, 1506.  [doi]    

Recent Synthetic Study towards Natural Products via (5+2) Cycloaddition

Liu, X.; Hu, Y.-J.; Fan, J.-H. Zhao, J.*; Li, S.*; Li, C.-C.*

Org. Chem. Front., 2018, 5, 1217.  [doi]

Catalytic Asymmetric Total Synthesis of Myrtucommuacetalones and Callistrilones 

Cheng, M.; Cao, J.; Yang, X.; Zhong, L.; Hu, L.; Lu, X.; Hou, B.; Hu, Y.; Wang, Y.; You, X.; Wang, L.*; Ye, W.-C.*; Li, C.-C.* 

Chem. Sci., 2018, 9, 1488.  [doi] 

• Highlighted in Royal Society of Chemistry, December, 2017.

• Highlighted in SUSTech NEWS, December, 2017.

Asymmetric Total Syntheses of Colchicine, beta-Lumicolchicine and Allocolchicinoid NCME

Liu, X.; Hu, Y.-J.; Chen, B. Min, L.; Peng, X.-S.; Zhao, J.*; Li, S.*;

Wong, H. N. C.; Li, C.-C.*

Org. Lett., 2017, 19, 4612.  [doi]

ACS Editors' Choice

• Top 1 Most Accessed Article in 08-09/2017.

• Top 5 Most Accessed Article in 08/2017-09/2018.

Enantioselective Total Synthesis of (-)-Colchicine, (+)-Demecolcinone and Metacolchicine

Chen, B.; Liu, X.; Hu, Y.-J.; Zhang, D.-M.; Deng, L.J.; Lu, J.Y.; Min, L.; Ye, W.-C.; Li, C.-C.*

Chem. Sci., 2017, 8，4961.  [doi]
 

Toward the Total Synthesis of Eurifoloid A

Liu, X.; Liu, J.Y.; Zhao, J.*; Li, S.*; Li, C.-C.*

Org. Lett., 2017, 19, 2742.  [doi] 

• Top 20 Most Accessed Article in 06/2017.

Synthetic Study toward the Total Synthesis of Solanoeclepin A

Liu, G.; Han, J.-C.; Li, C.-C.*

Tetrahedron., 2017, 73, 3629.  [doi] 

Recent Progress toward the Total Synthesis of Humulanolides

Han, J.-C.; Liu, X.; Zhao, J.; Li, S.; Li, C.-C.*

Tetrahedron., 2017, 73, 3289.  [doi] 

Catalytic Enantioselective Total Synthesis of Hypocrolide A

Qiao, C.; Zhang, W.; Han, J.; Li, C.-C.*

Org. Lett., 2016, 18, 4932.  [doi]

• Top 10 Most Accessed Article in 10/2016. 

• Top 20 Most Accessed Article in 09/2016-08/2017. 

Ruthenium-Catalyzed Metathesis Cascade Reactions in Natural Products Synthesis

Han, J.; Li, C.-C.*

The Chemial Record.,  2017, 499.  [doi]

•  An invited Account article.

Collective Synthesis of Natural Products Using Metathesis Cascade Reactions

Han, J.; Li, C.-C.*

Synlett., 2015, 26, 1289.  [doi] 

•  An invited Account article.    

Type II Intramolecular [5+2] Cycloaddition: Facile Synthesis of Highly Functionalized Bridged Ring Systems

Mei, G.; Liu, X.; Qiao, C.; Chen, W.; Li, C.-C.*

Angew. Chem. Int. Ed., 2015, 54, 1754.  [doi]

• Highlighted in SUSTech NEWS, 2014.

• Highlighted in Angew Cover, 2015.

Collective Synthesis of Humulanolides Using a Metathesis Cascade Reaction

Han, J.; Li, F.; Li, C.-C.*

J. Am. Chem. Soc., 2014, 136, 13610.  [doi]

•  Highlighted in Synfacts, 2014, 10, 1234.

•  Highlighted in Chemicals & Chemistry, 2014, Pubz ID: 009477592.

•  Highlighted in SUSTech NEWS, 2014.
•  Highlighted in ChemInform, March, 2015.

Dearomative Indole [5+2] Cycloaddition Reactions: Stereoselective Synthesis of Highly Functionalized Cyclohepta[b]indoles

Mei, G.; Yuan, H.; Gu, Y.; Chen, W.; Chung, L.; Li, C.-C.*

Angew. Chem. Int.Ed., 2014, 53, 11051.  [doi]

• Highlighted in Chin. J. Org. Chem., December, 2014.

• Highlighted in ChemInform, March, 2015.

Total Synthesis of Aplykurodinone-1

Liu, G.; Mei, G.; Chen, R.; Yuan, H.; Yang, Z.*; Li, C.-C.*

Org. Lett., 2014, 16, 4380.  [doi]

• Top 10 Most Accessed Article in 08/2014.

• Highlighted in ChemInform, Februry, 2015.

• Top 20 Most Accessed Article in 08/2014-06/2015.

Stereoselective Total Syntheses of (−)-Flueggine A and (+)-Virosaine B

Wei, H.; Qiao, C.; Liu, G.; Yang, Z.*; Li, C.-C.*

Angew. Chem. Int. Ed., 2013, 52, 620.  [doi]

• Chosen as “Hot Paper” by the Editors.

• Top 3 Most Accessed Article in 11/2012.

• Highlighted in PKUSZ NEWS, 2012.

• Highlighted in Chemistry World, January, 2013.

• Highlighted in Synfacts, 2013, 9, 237 (“Synfact of the Month”).

Total Synthesis of (±)-Pentalenolactone A Methyl Ester

Liu, Q.; Yue, G.; Wu, N.; Lin, G.; Li, Y.; Quan, J.; Li, C.-C.*; Wang, G.*; Yang, Z.*

Angew. Chem. Int. Ed., 2012, 51, 12072.  [doi]

• Top 10 Most Accessed Article in 10/2012.

• Highlighted in Chin. J. Org. Chem., January, 2013.

• Highlighted in Chemistry World, November, 2012.

Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes

Yue, G.; Zhang, Y.; Fang, L.; Li, C.-C.; Luo, T.*; Yang, Z.*

Angew. Chem. Int. Ed., 2014, 53, 1837.  [doi]

Development of an Expedient Intramolecular Pauson-Khand Reaction  Approach to Stereoselectively Construct the  trans-Decalin with C1 Quaternary Chiral Center

Shi, L.; Shen, H.; Fang, L.; Huang, J.; Li, C.-C.*; Yang, Z.*

Chem. Commun., 2013,49, 8806.  [doi]

Asymmetric Total Synthesis of (+)-Fusarisetin A via the Intramolecular Pauson-Khand Reaction

Huang, J.; Fang, L.; Long, R.; Shi, L.; Shen, H.; Li, C.-C.*; Yang, Z.*

Org. Lett., 2013, 15, 4018.  [doi]

• Top10 Most Accessed Article in 07/2013.

• Highlighted in Synfacts, 2014, 10, 8.

Asymmetric Total Synthesis of Caribenol A via an Intramolecular Diels–Alder Reaction

Han, J.; Liu, L.; Chang, Y.; Yue, G.; Guo, J.; Zhou, L.; Li, C.-C. *; Yang, Z.*

J. Org. Chem., 2013, 78, 5492.  [doi]

• Highlighted in Synfacts, 2013, 9, 809.

• Highlighted in Org. Chem. Highlights, December, 2013.

Asymmetric, Protecting-Group-Free Total Synthesis of (+)-Caribenol A

Han, J.; Liu, L.; Li, C.-C. *; Yang, Z.*

Chem. Asian J., 2013, 8, 1972.  [doi]

Reverse Regioselectivity in the Palladium(II) Thiourea Catalyzed Intermolecular Pauson–Khan Reaction

Wu, N.; Deng, L.; Liu, L.; Liu, Q.; Li, C.-C.*; Yang, Z.*

Chem. Asian J., 2013, 8, 65.  [doi]

Stereoselective Total Syntheses of (−)-Flueggine A and (+)-Virosaine B

Wei, H.; Qiao, C.; Liu, G.; Yang, Z.*; Li, C.-C.*

Angew. Chem. Int. Ed., 2013, 52, 620.  [doi]

• Chosen as “Hot Paper” by the Editors.

• Top 3 Most Accessed Article in 11/2012.

• Highlighted in PKUSZ NEWS, 2012.

• Highlighted in Chemistry World, January, 2013.

• Highlighted in Synfacts, 2013, 9, 237 (“Synfact of the Month”).

Synthesizing the Tetracyclic Core of Nanolobatolide

Chang, L.; Jiang, H.; Fu, J.; Liu, B.; Li, C.-C.*; Yang, Z.*

J. Org. Chem., 2012, 77, 3609.  [doi]

Total Synthesis of (±)-Pentalenolactone A Methyl Ester

Liu, Q.; Yue, G.; Wu, N.; Lin, G.; Li, Y.; Quan, J.; Li, C.-C.*; Wang, G.*; Yang, Z.*

Angew. Chem. Int. Ed., 2012, 51, 12072.  [doi]

• Top 10 Most Accessed Article in 10/2012.

• Highlighted in Chin. J. Org. Chem., January, 2013.

• Highlighted in Chemistry World, November, 2012.

InCl3-mediated  intramolecular Friedel-Crafts-type cyclization and its application to construct the [6-7-5-6] tetracyclic scaffold of liphagal

Jiang, H.; Tian, L.; Li, Z.; Liu, Q.; Li, C.-C.*; Yao, X.* ; Yang, Z.*

Science China Chemistry., 2012, 50, 36.  [doi]

A Concise Approach for the Total Synthesis of Pseudolaric acid A

Xu, T.; Li, C.-C.*; Yang, Z.*

Org. Lett., 2011,13, 2630.  [doi]

• “Highlight syntheses” in Annu. Rep. Prog. Chem., Sect. B: Org. Chem., 2012.

Total Syntheses of Drimane-Type Sesquiterpenoids Enabled by a Gold-Catalyzed Tandem Reaction

Shi, H.; Fang, L.; Tan, C.; Shi, L.; Zhang, W.; Li, C.-C.*; Luo, T.*; Yang, Z.*

J. Am. Chem. Soc., 2011, 133, 14944.  [doi]

• Highlighted in Org. Chem. Highlights, August, 2012.

Fomal Synthesis of Cortistatins

Fang, L.; Chen, Y.; Huang, J.; Liu, L.; Li, C.-C.*; Yang, Z* .

J. Org. Chem., 2011, 76, 2479.  [doi]

A Thiourea-Oxazoline Library with Axial Chirality: Ligand Synthesis and  Studies of the Palladium-Catalyzed EnantioselectiveBis(methoxycarbonylation) of Terminal Olefins

Gao, Y.; Chang, L.; Shi, H.; Liang, B.; Wongkhan, K.; Chaiyaveij, D.; Batsanov, A.; Marder,T.; Li,C.-C.*; Yang, Z.*; Huang, Y*.

Adv. Synth. Catal., 2010, 352, 1955.  [doi]

Total Synthesis of (±) Maoecrystal V

Gong, J.; Lin, G.; Sun, W.; Li, C.-C.*; Yang, Z.*

J. Am. Chem. Soc., 2010, 132, 16745.  [doi]

• Top3 Most Accessed Article in J. Am. Chem. Soc. of 2010.

• Highlighted in Nature, December, 2010.

• Highlighted in Chemistry World, December, 2010.

• Highlighted in Synfacts, 2011, 3, 239 (“Synfact of the Month”).

• Highlighted in Org. Chem. Highlights, June, 2011.

Asymmetric Total Synthesis of Caribenol A

Liu, L.; Han, J.; Yue, G.; Li, C.-C.*; Yang, Z.*

J. Am. Chem. Soc., 2010, 132, 13608.  [doi]

• Top5 Most Accessed Article in J. Am. Chem. Soc. of 2010.

• Highlighted in Nature Chemistry, September, 2010.

• Highlighted in Chin. J. Org. Chem., November, 2010.

• “Highlight syntheses” in Annu. Rep. Prog. Chem., 2011.

• Highlighted in Org. Chem. Highlights, August, 2011.

Synthetic Study toward the Total Synthesis of Maoecrystal V

Gong, J.; Lin, G.; Li, C.-C.*; Yang, Z* .

Org. Lett., 2009, 11, 4770.  [doi]

Concise  Synthesis of the CortistatinsOxatetracyclic Core through Intramolecular  Diels-Alder Reaction and OxidativeDearomatization Cyclization

Liu, L.; Gao, Y.; Che, C.; Wu, N.; Wang, D.; Li, C-C.*; Yang, Z*.

Chem. Commun., 2009, 662.  [doi]

Stereodivergent  Synthesis of 17-a and 17-b-Aryl Steroids: Application and Biological  Evaluation  of D-Ring Cortistatin Analogues

Shi, J.; Shigehisa, H.; Guerrero, C.; Shenvi, R.; Li, C.-C.; Baran, P.

Angew. Chem. Int. Ed., 2009, 48, 4328.  [doi]

Synthesis of (+)-Cortistatin A

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•#1 Most Accessed Article in J. Am. Chem. Soc. for all of 2008.

• Highlighted in Nature Chemistry, May 2008.

•Highlighted in Chemical & Engineering News, 86 (21), May 2008.

• Highlighted in Angew. Chem. Int. Ed. 2008, 47, 9389–9391.

•“SynFact of the Month”, Synfacts, 2008, 11, 1127.

Synthetic  Study of 1,3-Butadiene-Based IMDA Approach to Construct a [5-7-6]  Tricyclic Core and Its Application to the Total Synthesis of  C8-epi-Guanacastepene O

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Exploring Expedient IMDA Reaction Approach to Construct the anacastepenes’s Core

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Org. Lett., 2005, 7, 3709.  [doi]

Total Synthesis of Wedelolactone

Li, C. C.; Xie, Z. X.; Zhang, Y. D.; Chen, J. H.; Yang, Z.

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Compounding Method of Maoecrystal

Yang, Z.; Li, C.-C.; Gong, J.

Chinese Patent: CN101974013.

Total Synthesis of Flueggine A, Norsecurinine, Virosaine B and Allonorsecurinine

Li, C.-C.; Yang, Z.; Wei, H.

Chinese Patent: CN103059034A.

Compounding Method of Cladiellin and Pachycladin D

Yue, G.; Zhang, Y.; Li, C.-C.; Luo, T.;Yang, Z.

Chinese Patent: CN201310400640.

Total Synthesis of Antrocin

Shi, H.; Shi, L.; Zhang, W.; Li, C.-C.; Yang, Z.

Chinese Patent: CN201100664899.

Method for chemical synthesis of antrocin and use thereof for suppressing non-small cell lung cancer

Yang, Z.; Tzeng, Y.; Li, C.-C.; Luo, T.; Shi, H.; Yeh, C.;

Patent: WO2013020285 A1.

Synthesis of (+) Corstistatin A and Related Compounds

Shenvi, R. A.; Guerrero, C. A.; Shi, J.; Li, C. C.; Baran, P. S.

Wipo Patent: WO/2009/137335.

Stereoselective Synthesis of 17-α and 17-β-Aryl Steroidal Compounds

Shi, J.; Shigehisa, H.; Guerrero, C. A.; Shenvi, R. A.; Li, C.-C.; Baran, P. S.

International Patent Application No. PCT/US09/42404.

Total Synthesis of Wedelolactone and Application

Li, C.-C.; Xie, Z. X.; Chen, J. H.; Yang, Z.

Chinese Patent: CN031465846.